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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCI
All Species:
27.88
Human Site:
S123
Identified Species:
43.81
UniProt:
P41743
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41743
NP_002731.4
596
68262
S123
P
C
P
G
E
D
K
S
I
Y
R
R
G
A
R
Chimpanzee
Pan troglodytes
XP_001148501
597
67369
N129
W
R
K
L
Y
C
A
N
G
H
L
F
Q
A
K
Rhesus Macaque
Macaca mulatta
XP_001089400
597
68263
S124
P
C
P
G
E
D
K
S
I
Y
R
R
G
A
R
Dog
Lupus familis
XP_535855
696
78257
S223
P
C
P
G
E
D
K
S
I
Y
R
R
G
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q62074
595
68185
S123
P
C
P
G
E
D
K
S
I
Y
R
R
G
A
R
Rat
Rattus norvegicus
P09217
592
67715
I114
C
P
G
E
D
K
S
I
Y
R
R
G
A
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506164
360
41199
Chicken
Gallus gallus
XP_417561
606
69931
S127
P
C
P
G
E
D
K
S
I
Y
R
R
G
A
R
Frog
Xenopus laevis
NP_001084068
588
67442
S116
P
C
T
G
E
D
K
S
I
Y
R
R
G
A
R
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
S116
P
C
P
G
E
D
K
S
I
Y
R
R
G
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
S165
T
F
C
D
H
C
G
S
L
L
Y
G
L
I
K
Honey Bee
Apis mellifera
XP_397273
590
68031
R114
E
D
R
S
I
Y
R
R
G
A
R
R
W
R
K
Nematode Worm
Caenorhab. elegans
Q19266
597
68017
R117
T
V
Y
R
R
G
A
R
R
W
K
K
I
Y
L
Sea Urchin
Strong. purpuratus
XP_780275
524
59689
H94
V
D
C
K
L
L
V
H
K
K
C
H
R
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P87253
1142
127954
G440
P
Q
G
M
D
R
L
G
R
K
G
A
V
R
Q
Conservation
Percent
Protein Identity:
100
66.6
96.8
84.3
N.A.
98.3
72.3
N.A.
59.9
71.4
89.7
88.7
N.A.
36.4
67.9
58.1
63.5
Protein Similarity:
100
78.5
97.4
84.9
N.A.
98.8
83.5
N.A.
60.4
83
94.4
92.9
N.A.
54
78.1
74.1
72.4
P-Site Identity:
100
6.6
100
100
N.A.
100
13.3
N.A.
0
100
93.3
100
N.A.
6.6
13.3
0
0
P-Site Similarity:
100
26.6
100
100
N.A.
100
20
N.A.
0
100
93.3
100
N.A.
20
26.6
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
23.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
14
0
0
7
0
7
7
54
0
% A
% Cys:
7
47
14
0
0
14
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
14
0
7
14
47
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
7
47
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
0
14
47
0
7
7
7
14
0
7
14
47
0
0
% G
% His:
0
0
0
0
7
0
0
7
0
7
0
7
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
7
47
0
0
0
7
7
0
% I
% Lys:
0
0
7
7
0
7
47
0
7
14
7
7
0
0
20
% K
% Leu:
0
0
0
7
7
7
7
0
7
7
7
0
7
7
7
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
54
7
40
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
7
% Q
% Arg:
0
7
7
7
7
7
7
14
14
7
60
54
7
20
54
% R
% Ser:
0
0
0
7
0
0
7
54
0
0
0
0
0
0
0
% S
% Thr:
14
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
7
0
0
0
0
7
0
0
0
0
0
7
0
7
% V
% Trp:
7
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% W
% Tyr:
0
0
7
0
7
7
0
0
7
47
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _